Successful medical management of the organ donor helps support potential donors and their families achieve their goal of donating as many organs as possible, in the best condition possible. Close adherence to donor management guidelines may help streamline care and optimize outcomes. In this module, participants will learn how to: 1. Describe investigations required to ensure medical suitability of organs recovered for transplantation. 2. Explain the pathophysiology behind conditions that lead to hemodynamic instability in the potential organ donor. 3. Understand how to implement the Canadian guidelines for medical management of donors following determination of death by neurologic criteria.