The information in this chapter is supported by the literature, by expert opinion, and, most importantly, by interviews with family members who have been directly involved in decision-making related to organ donation and subsequent events. It incorporates their experiences, the problems they encountered, and the approaches they have suggested. A major objective of this chapter is to: 1. Describe the needs of families at different times in the donation process. 2. Offer communication strategies and support tailored to these needs.